By Margaret Barton-Burke, Gail M. Wilkes, Karen C. Ingwersen, Catherine K. Bean, Deborah Berg
Oncology Consulting providers, Boston, MA. moment variation of a scientific reference for practitioners. prior variation 1991. Emphasizes the nursing procedure, together with analysis and care plans. Concise structure. wide use of charts. thirteen U.S. members. DNLM: Neoplasms - nursing.
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Additional info for Cancer Chemotherapy: A Nursing Process Approach (Jones and Bartlett Series in Nursing)
The static-appearing care plans, based on the American Nurses Association (ANA)/Oncology Nursing Society (ONS) Standards for Oncology Nursing Practice, are intended to be guidelines adapted to the ever-changing needs of the client. However, the second edition of this book has intentionally broadened the conceptualizations of chemotherapy, nursing care, and the client. The increased knowledge of the biologic processes that result in cancer combined with the ability to modify these biologic responses permit oncology nurses to rethink the extent of cancer Page xii chemotherapy.
3). An article by Gross (1986) contains a diagram that describes the number of compounds that are initially reviewed compared with the actual number of compounds that make it to toxicity studies (clinical trials). 1 shows, only a handful of drugs make it to clinical trials after several years of reviewing and screening. By the time a drug becomes available to the general medical community, it has gone through extensive testing for toxicity in both animals and humans. Federal law mandates that any new drug considered for use in humans must undergo thorough toxicity testing in animals first (Carter 1977).
At the end of the phase II study, there should be adequate information on efficacy and the nature of toxicities to justify further study. This justification for further study should be based on the concept of a risk-benefit ratio. Phase III Clinical Trials The goal of phase III is to establish the new drug as an effective treatment by comparing it with conventional treatments (Lake and Jenkins 1993). Patients are randomized in a phase III study in an effort to eliminate any conscious or unconscious investigator bias.