Apoptosis Senescence and Cancer by David A Gewirtz (Editor), Shawn Edan Holt (Editor), Steven

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By David A Gewirtz (Editor), Shawn Edan Holt (Editor), Steven Grant (Editor)

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Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome C. Cell 1996; 86(1):147–57. 60. Kluck RM, Martin SJ, Hoffman BM, Zhou JS, Green DR, Newmeyer DD. Cytochrome C activation of CPP32-like proteolysis plays a critical role in a xenopus cell-free apoptotis system. EMBO J 1997; 16(15):4639–49. 22 Part I / Apoptosis and Alternative Modes of Cell Death 61. Hampton MB, Zhivotovsky B, Slater AF, Burgess DH, Orrenious S. Importance of the redox state of cytochrome C during caspase activation in cytosolic extracts.

J Biol Chem 2001; 276(15):11615–23. 81. Desagher S, Osen-Sand A, Nichols A, et al. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome C release during apoptosis. J Cell Biol 1999; 144(5):891–901. 82. Eskes R, Desagher S, Antonsson B, Martinou JC. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol Cell Biol 2000; 20:929–35. 83. Makin GWJ, Corfe BM, Griffiths GJ, Thistlethwaite A, Hickman JA, Dive C. Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate.

133. Deng X, Gao F, Flagg T, May WS Jr. Mono- and multisite phosphorylation enhances Bcl2’s antiapoptotic function and inhibition of cell cycle entry functions. Proc Natl Acad Sci USA 2004; 101(1):153–8. Chapter 1 / The Intrinsic Pathway of Apoptosis 25 134. Domina AM, Smith JH, Craig RW. Myeloid cell leukemia 1 is phosphorylated through two distinct pathways, one associated with extracellular signal-regulated kinase activation and the other with G2/M accumulation or protein phosphatase 1/2A inhibition.

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